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Estradiol Shortage UK 2026

Current supply status and alternatives for Estradiol

Source data checked 12 November 2026, 06:18 UTC
Shortage

Active shortage affecting some presentations — official DHSC / NHSBSA data list a current shortage for: Estradot® 25 microgram patches (SSP082); Estradot® 100 microgram patches (SSP081); Estradot® 75 microgram patches (SSP080); Estradot® 50 microgram patches (SSP079) (official data last checked 12 November 2026, 06:18 UTC). Other forms of Estradiol may not be affected — check with your pharmacy before travelling.

Estradot® 25 microgram patches

Shortage

Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

From the official notice: NHSBSA SSP082, issued 03 April 2025.

Estradot® 100 microgram patches

Shortage

Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

From the official notice: NHSBSA SSP081, issued 19 December 2024.

Estradot® 75 microgram patches

Shortage

Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

From the official notice: NHSBSA SSP080, issued 19 December 2024.

Estradot® 50 microgram patches

Shortage

Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

From the official notice: NHSBSA SSP079, issued 19 December 2024.

Don't stop or change your medicine on your own. Ask your pharmacist or GP.

Not medical advice. MediWatch reports official UK medicine supply data; it is not a substitute for advice from a pharmacist, GP or prescriber. Do not stop, change or switch a medicine without speaking to them first. If you are unwell, contact NHS 111, or call 999 in an emergency. How we check our information.

Track Estradiol

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Nearby pharmacies to call about Estradiol

Enter your postcode to see nearby NHS-registered pharmacies. Stock is not confirmed.

MediWatch does not guarantee live local stock. Call the pharmacy to confirm before travelling, and never stop or change medication without medical advice.

Where to get Estradiol

  1. Speak to your pharmacist. They may be able to order it from another wholesaler, or suggest a different strength or form.
  2. Ask your GP or prescriber about an alternative if it can't be sourced. Don't stop or switch medicine on your own.
  3. Try other pharmacies. Stock varies between pharmacies. Find nearby pharmacies to call or use the NHS Find a pharmacy service (opens in a new tab).
⚠️ Our data shows national supply status from DHSC, NHSBSA and MHRA. Your local pharmacy may still be temporarily out of stock due to delivery schedules or local demand. Always check with your pharmacist.
Estradiol is used for hormone replacement therapy for menopause symptoms (source: NHS medicines A to Z). Official DHSC / NHSBSA data list 4 active shortage notifications for Estradot® 25 microgram patches; Estradot® 100 microgram patches; Estradot® 75 microgram patches; and 1 more. Other forms of this medicine are not named in them — details above.

What to Do If You're Affected

Frequently Asked Questions

Is Estradiol in shortage in the UK in 2026?

Official DHSC / NHSBSA data list 4 active shortage notifications for Estradot® 25 microgram patches; Estradot® 100 microgram patches; Estradot® 75 microgram patches; and 1 more. Other forms of Estradiol are not named in them. Sign up for MediWatch alerts to be notified of any changes.

What is Estradiol used for?

Estradiol is commonly prescribed in the UK for hormone replacement therapy for menopause symptoms. It is dispensed through NHS pharmacies across the country.

What should I do if I can't get Estradiol from my pharmacy?

Ask your pharmacist whether a Serious Shortage Protocol (SSP) covers it and what that protocol allows: each one sets out exactly what can be supplied. If not, contact your GP who can prescribe a suitable alternative. Try other local pharmacies as stock levels vary by location.

What are the alternatives to Estradiol?

Your GP may consider alternatives including other estradiol brands, conjugated estrogens, tibolone. Always consult your doctor or pharmacist before switching medications.

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Data sources: DHSC Medicine Supply Notifications · NHSBSA Serious Shortage Protocols · MHRA alerts
Page last updated: 1 November 2026. Data checked daily.