Medicine Shortage UK 2026 — Complete List

Updated 7 February 2026 from official DHSC & NHS data
There are currently 212 active medicine shortages in the UK, tracked from official DHSC Medicine Supply Notifications and NHSBSA Serious Shortage Protocols. This page is updated daily.

All Active Shortages

Co-trimoxazole 40mg/200mg/5ml oral suspension sugar free and Co-trimoxazole 80mg/400mg/5ml oral suspension

high DHSC MSN

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Supply issues with multiple GLP-1 RA products

high DHSC MSN

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Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution for injection ampoules

high DHSC MSN

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Expected resolution: December 2024

Antimicrobial Agents Used in Tuberculosis (TB) Treatment

high DHSC MSN

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Diamorphine 5mg, 10mg and 100mg powder for solution for injection ampoules

High DHSC MSN

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Estradot® 25 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 25 microgram patches (PDF:218KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 03 April 2025

Estradot® 100 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100 microgram patches (PDF:215KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Estradot® 75 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 75 microgram patches (PDF:219KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Estradot® 50 microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 50 microgram patches (PDF:219KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2024

Creon® 25000 capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Creon® 25000 capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 24 May 2024

Creon® 10000 capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Creon® 10000 capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 24 May 2024

Latanoprost 50micrograms/ml / Timolol 5mg/ml (Fixapost®) eye drops 0.2ml unit dose preservative free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Latanoprost 50micrograms/ml / Timolol 5mg/ml (Fixapost®) eye drops 0.2ml unit dose preservative free (PDF:193KB). Pharmacists may supply alternatives without GP re

Expected resolution: 19 December 2025

Adipine® XL 60mg MR tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Adipine® XL 60mg MR tablets (PDF:199KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2025

Venlafaxine 37.5mg modified release tablet

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Venlafaxine 37.5mg modified release tablet (PDF:156KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 23 June 2025

Cefalexin 250mg/5ml oral suspension sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Cefalexin 250mg/5ml oral suspension sugar free (PDF:143KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 08 May 2025

Cefalexin 125mg/5ml oral suspension sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Cefalexin 125mg/5ml oral suspension sugar free (PDF:143KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 10 December 2024

Nyzamac® SR 60mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Nyzamac® SR 60mg capsules (PDF:162KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 September 2024

Monomil® XL 60mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Monomil® XL 60mg tablets (PDF:162KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 September 2024

Monomax® XL 60mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Monomax® XL 60mg tablets (PDF:162KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 September 2024

Chemydur® 60XL tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Chemydur® 60XL tablets (PDF:163KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 September 2024

Cefalexin 500mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Cefalexin 500mg tablets (PDF:138KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 August 2024

Ramipril 2.5mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Ramipril 2.5mg tablets (PDF:139KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 06 August 2024

Quetiapine 300mg tablets substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 300mg tablets substitution and restriction (PDF:201KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 300mg tablets restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 300mg tablets restriction (PDF:202KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 300mg tablets substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 300mg tablets substitution (PDF:204KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 200mg tablets substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 200mg tablets substitution and restriction (PDF:203KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 200mg tablets restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 200mg tablets restriction (PDF:202KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 200mg tablets substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 200mg tablets substitution (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 150mg tablets substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 150mg tablets substitution and restriction (PDF:204KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 150mg tablets restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 150mg tablets restriction (PDF:203KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Quetiapine 150mg tablets substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Quetiapine 150mg tablets substitution (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 July 2024

Monomil® XL 60mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Monomil® XL 60mg tablets (PDF:164KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 26 Mar 2024

Jext® 300micrograms/0.3ml (1 in 1000) solution for injection auto-injector pen

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Jext® 300micrograms/0.3ml (1 in 1000) solution for injection auto-injector pen (PDF:200KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 1 in 1000

Estradot® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100mcg patches (PDF:218KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 21 Aug 2023

Utrogestan® 100mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Utrogestan® 100mg capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2023

Estradot® 75mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 75mcg patches (PDF:216KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 13 Apr 2023

Clarithromycin 250mg/5ml oral suspension

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Clarithromycin 250mg/5ml oral suspension (PDF:150KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 22 May 2024

Clarithromycin 125mg/5ml oral suspension

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Clarithromycin 125mg/5ml oral suspension (PDF:147KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 22 May 2024

Progynova® TS 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Progynova® TS 100mcg patches (PDF:217KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 28 Mar 2023

Paracetamol 240mg suppositories

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Paracetamol 240mg suppositories (PDF:142KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 17 Mar 2023

Paracetamol 120mg suppositories

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Paracetamol 120mg suppositories (PDF:143KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Feb 2023

Estradot® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 100mcg patches (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 25 Jan 2023

Estradot® 50mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot® 50mcg patches (PDF:205KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 25 Jan 2023

Phenoxymethylpenicillin 250mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 250mg tablets (PDF:272KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Dec 2022

Phenoxymethylpenicillin 250mg/5ml oral solution sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 250mg/5ml oral solution sugar free (PDF:274KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Dec 2022

Phenoxymethylpenicillin 250mg/5ml oral solution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 250mg/5ml oral solution (PDF:274KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Dec 2022

Phenoxymethylpenicillin 125mg/5ml oral solution sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 125mg/5ml oral solution sugar free (PDF:275KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Dec 2022

Phenoxymethylpenicillin 125mg/5ml oral solution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 125mg/5ml oral solution (PDF:273KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Dec 2022

Phenoxymethylpenicillin 250mg/5ml oral solution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 250mg/5ml oral solution (PDF:143KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Dec 2022

Phenoxymethylpenicillin 250mg/5ml oral solution sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 250mg/5ml oral solution sugar free (PDF:145KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Dec 2022

Phenoxymethylpenicillin 125mg/5ml oral solution sugar free

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Phenoxymethylpenicillin 125mg/5ml oral solution sugar free (PDF:138KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Dec 2022

atorvastatin (Lipitor®)20mg chewable tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for atorvastatin (Lipitor®)20mg chewable tablets (PDF:150KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 23 Nov 2022

Estraderm MX® 75mcg patches substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 75mcg patches substitution (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Nov 2022

Estraderm MX® 50mcg patches substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 50mcg patches substitution (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Nov 2022

Estraderm MX® 100mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 100mcg patches (PDF:214KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 08 Sep 2022

Estraderm MX® 25mcg patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estraderm MX® 25mcg patches (PDF:213KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 08 Sep 2022

Combisal® 125mcg/25mcg inhalers

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Combisal® 125mcg/25mcg inhalers (PDF:146KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 22 Jul 2022

Paracetamol 120mg suppositories

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Paracetamol 120mg suppositories (PDF:139KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 31 May 2022

Atorvastatin (Lipitor®) 10mg chewable tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Atorvastatin (Lipitor®) 10mg chewable tablets (PDF:145KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 31 May 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution and restriction (PDF:751KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets substitution (PDF:751KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Sandrena®) 0.5mg and 1mg gel sachets restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Sandrena®) 0.5mg and 1mg gel sachets restriction (PDF:600KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution and restriction (PDF:749KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray substitution (PDF:748KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Lenzetto®)1.53mg/dose transdermal spray restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Lenzetto®)1.53mg/dose transdermal spray restriction (PDF:601KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estriol (Ovestin® 1mg cream) 0.1% cream substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estriol  (Ovestin® 1mg cream) 0.1% cream substitution and restriction (PDF:228KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estriol (Ovestin® 1mg cream) 0.1% cream substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estriol  (Ovestin® 1mg cream) 0.1% cream substitution (PDF:226KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 May 2022

Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution and restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution and restriction (PDF:751KB). Pharmacists may supply alternatives wit

Expected resolution: 19 May 2022

Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradiol (Oestrogel® Pump-Pack 0.06% gel) 0.06% gel (750microgram per actuation) substitution (PDF:750KB). Pharmacists may supply alternatives without GP referral

Expected resolution: 19 May 2022

Premique® low dose 0.3mg/1.5mg modified-release tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Premique® low dose 0.3mg/1.5mg modified-release tablets (PDF:166KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Apr 2022

Ovestin® 1mg cream restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Ovestin® 1mg  cream restriction (PDF:166KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Apr 2022

Oestrogel® Pump-Pack 0.06% gel restriction

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Oestrogel®  Pump-Pack 0.06% gel restriction (PDF:167KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Apr 2022

Salazopyrin® 500mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin® 500mg tablets (PDF:244KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 16 Mar 2022

Atorvastatin (Lipitor®) 20mg chewable tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Atorvastatin (Lipitor®) 20mg chewable tablets (PDF:122KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Feb 2022

Atorvastatin (Lipitor®) 10mg chewable tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Atorvastatin (Lipitor®) 10mg chewable tablets (PDF:123KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 15 Feb 2022

Paracetamol 120mg and 240mg suppositories

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Paracetamol 120mg and 240mg suppositories (PDF:124KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 25 Jan 2022

Salazopyrin® 500mg EN tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin® 500mg EN tablets (PDF:160KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 26 Nov 2021

Atorvastatin (Lipitor®) 20mg chewable tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Atorvastatin (Lipitor®) 20mg chewable tablets (PDF:211KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 18 Nov 2021

Estradot® 75microgram patches

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Estradot®  75microgram patches (PDF:204KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Apr 2021

Competact 15mg/850mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Competact 15mg/850mg tablets (PDF:170KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 24 Mar 2021

Levothyroxine 12.5microgram tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Levothyroxine 12.5microgram tablets (PDF:143KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Feb 2021

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:139KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 29 Jan 2021

Salazopyrin 500mg EN tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin 500mg EN tablets (PDF:151KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 20 Oct 2020

Fluoxetine 30mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 30mg capsules (PDF:144KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 20 Oct 2020

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:135KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 20 May 2020

Fluoxetine 10mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 10mg tablets (PDF:134KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 12 Mar 2020

Haloperidol (Serenace) 500 microgram (mcg) capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Haloperidol  (Serenace) 500 microgram (mcg) capsules (PDF:107KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 23 Dec 2019

Fluoxetine 40mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 40mg capsules (PDF:131KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Fluoxetine 30mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 30mg capsules (PDF:124KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Fluoxetine 10mg capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Fluoxetine 10mg capsules (PDF:151KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 3 Oct 2019

Rivastigmine 4.6mg/24hours and 9.5mg/24hours transdermal patches

high DHSC MSN

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Co-codamol 30mg/500mg tablets

High DHSC MSN

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Flixotide® (fluticasone) 50 micrograms/dose Evohaler

medium DHSC MSN

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Nadolol 80mg tablets

medium DHSC MSN

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Oxcarbazepine 150mg and 300mg tablets

medium DHSC MSN

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Formoterol (Oxis® 6 Turbohaler) 6micrograms/dose dry powder inhaler

medium DHSC MSN

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Creon® 25,000 gastro-resistant capsules

medium DHSC MSN

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Epilim® (sodium valproate) syrup 200mg/5ml

medium DHSC MSN

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Midazolam (Epistatus® ) 5mg/0.5ml oromucosal solution pre-filled oral syringes

medium DHSC MSN

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Salbutamol 2.5mg/2.5ml nebuliser liquid unit dose vials

medium DHSC MSN

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Prochlorperazine (Stemetil®) 12.5mg/ml solution for injection ampoules

medium DHSC MSN

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Jext® 300micrograms/0.3ml (adrenaline 1 in 1000) solution for injection auto-injector pen

medium DHSC MSN

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Insulatard® InnoLet® (insulin isophane human) 100units/ml suspension for injection 3ml pre-filled disposable devices

medium DHSC MSN

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Levemir InnoLet® (insulin detemir) 100units/ml solution for injection 3ml pre-filled disposable devices

medium DHSC MSN

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Isosorbide mononitrate (Monomil® XL) 60mg modified-release tablets

medium DHSC MSN

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Diazepam 10mg/2.5ml rectal solution tubes

medium DHSC MSN

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Guanfacine (Intuniv®) 2mg and 3mg modified-release tablets

medium DHSC MSN

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Phenobarbital 15mg tablets (Accord)

medium DHSC MSN

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Carbamazepine 100mg and 200mg tablets

medium DHSC MSN

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Cefalexin 125mg/5ml and 250mg/5ml oral suspension

medium DHSC MSN

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Naloxegol (Moventig® ) 12.5mg and 25mg tablets

medium DHSC MSN

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Mesalazine (Asacol® ) 400mg MR gastro-resistant tablets

medium DHSC MSN

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Expected resolution: April 2024

Daktacort® (hydrocortisone 1% / miconazole 2%) cream

medium DHSC MSN

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Sulfadiazine silver (Flamazine® ) 1% cream

medium DHSC MSN

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Tegretol® (carbamazepine) 100mg/5ml liquid

medium DHSC MSN

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Humulin® S (insulin soluble human) 100units/ml solution for injection 10ml vials

medium DHSC MSN

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Expected resolution: May 2024

Salbutamol 2.5mg/2.5ml and 5mg/2.5ml nebuliser liquid unit dose vials

medium DHSC MSN

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Clarithromycin 125mg/5ml and 250mg/5ml oral suspensions

medium DHSC MSN

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Expected resolution: May 2024

Nortriptyline 10mg/5ml and 25mg/5ml oral solution sugar-free

medium DHSC MSN

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Memantine (Valios® ) 10mg and 20mg orodispersible tablets sugar free

medium DHSC MSN

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Somatropin (NutropinAq® ) 10mg/2ml solution for injection cartridges Somatropin (Humatrope® ) 6mg, 12mg and 24mg powder and solvent for solution for injection cartridges

medium DHSC MSN

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Clomethiazole 192mg capsules

medium DHSC MSN

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Co-trimoxazole 40mg/200mg/5ml oral suspension sugar free

medium DHSC MSN

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Imiquimod (Aldara® ) 5% cream and podophyllotoxin (Warticon® ) 0.5% solution and 0.15% cream

medium DHSC MSN

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Erythromycin 250mg gastro-resistant tablets

medium DHSC MSN

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Humalog® (insulin lispro) 100units/ml solution for injection 10ml vials

medium DHSC MSN

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Triamcinolone acetonide suspension for injection vials (Kenalog® 40mg/1ml and Adcortyl® 50mg/5ml)

medium DHSC MSN

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Flixotide® (fluticasone) 125micrograms/dose and 250micrograms/dose Evohaler®

medium DHSC MSN

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Disopyramide (Rythmodan Retard® ) 250mg modified-release tablets and disopyramide (Rythmodan® ) 100mg capsules. Updated

medium DHSC MSN

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Ipratropium bromide 250micrograms/1ml and 500micrograms/2ml nebuliser liquid unit dose vials

medium DHSC MSN

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Quetiapine 150mg, 200mg, 300mg tablets

medium DHSC MSN

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Carbamazepine 100mg/5ml oral suspension sugar free (Accord)

medium DHSC MSN

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Ramipril 2.5mg tablets

medium DHSC MSN

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Expected resolution: October 2024

Desmopressin (DDAVP®) 4 micrograms/1ml solution for injection ampoules

medium DHSC MSN

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Cefalexin 500mg tablets

medium DHSC MSN

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Naltrexone 50mg tablets

medium DHSC MSN

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Norethisterone (Noriday® ) 350microgram tablets

medium DHSC MSN

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Naloxone (Nyxoid® ) 1.8mg/0.1ml nasal spray unit dose

medium DHSC MSN

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Trandolapril 2mg and 4mg capsules

medium DHSC MSN

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Nicorandil 10mg tablets

medium DHSC MSN

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Torasemide 10mg tablets

medium DHSC MSN

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Levobunolol (Betagan®) 0.5% eye drops 0.4ml unit dose preservative free

medium DHSC MSN

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Diclofenac (Voltarol® Ophtha Multidose) 0.1% eye drops

medium DHSC MSN

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Insulatard® (isophane insulin, human) Penfill® 100units/ml suspension for injection 3ml cartridges

medium DHSC MSN

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Expected resolution: June 2025

Coal tar extract (Neutrogena® T/Gel® Therapeutic) 2% shampoo

medium DHSC MSN

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Cefalexin 125mg/5ml and 250mg/5ml oral suspensions, sugar free

medium DHSC MSN

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Isosorbide mononitrate 10mg, 20mg and 40mg tablets (immediate-release)

medium DHSC MSN

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Prednisolone 20mg/100ml rectal solution

medium DHSC MSN

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Apomorphine hydrochloride (APO-go® PFS) 50mg/10ml solution for infusion pre-filled syringes

medium DHSC MSN

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Expected resolution: April 2025

NovoRapid® (insulin aspart) FlexTouch® 100units/ml solution for injection 3ml pre-filled pens

medium DHSC MSN

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Expected resolution: March 2025

Hydrocortisone sodium phosphate 100mg/1ml solution for injection ampoules

medium DHSC MSN

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Expected resolution: March 2025

Memantine (Valios® ) 5mg orodispersible tablets sugar free

medium DHSC MSN

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Triptorelin acetate (Gonapeptyl® Depot) 3.75mg powder and solvent for suspension for injection pre-filled syringes

medium DHSC MSN

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Megestrol (Megace®) 160mg tablets

medium DHSC MSN

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Salbutamol (Salamol Easi-Breathe®) 100micrograms/dose breath actuated inhaler CFC free

medium DHSC MSN

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Apraclonidine (Iopidine® ) 5mg/ml (0.5%) eye drops

medium DHSC MSN

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Diltiazem (Angitil® SR) 90mg modified-release capsules

medium DHSC MSN

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Estradiol (Estradot®) transdermal patches

medium DHSC MSN

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Galantamine 8mg, 16mg and 24mg modified-release capsules

medium DHSC MSN

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Triamcinolone acetonide 10mg/ml (Adcortyl® multi-dose vial) and 40mg/ml (Kenalog® vials) suspension for injection

medium DHSC MSN

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Expected resolution: June 2025

Fentanyl (Effentora® ) 200microgram, 400microgram, 600microgram, 800microgram buccal tablets Fentanyl (Actiq® ) 800microgram lozenges

medium DHSC MSN

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Fentanyl (Durogesic® DTrans®) patches

medium DHSC MSN

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Buprenorphine (Reletrans® ) 5micrograms/hour and 15micrograms/hour transdermal patches

medium DHSC MSN

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Lidocaine (Xylocaine® ) 10mg/dose spray sugar free

medium DHSC MSN

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Tolterodine 2mg and 4mg modified-release capsules

medium DHSC MSN

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Phenobarbital 15mg/5ml elixir

medium DHSC MSN

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NovoRapid® PumpCart® (insulin aspart) 100units/ml solution for injection 1.6ml cartridges

medium DHSC MSN

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Expected resolution: July 2025

Venlafaxine 37.5mg modified-release tablets

medium DHSC MSN

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Buprenorphine (Relevtec®) 35micrograms/hour, 52.5micrograms/hour, 70micrograms/hour transdermal patches Buprenorphine (Bupeaze®) 52.5micrograms/hour transdermal patches

medium DHSC MSN

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Betamethasone 500microgram soluble tablets sugar free

medium DHSC MSN

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Expected resolution: October 2025

Diclofenac (Voltarol® Ophtha) 0.1% eye drops 0.3ml unit dose preservative free

medium DHSC MSN

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Salbutamol 100micrograms/dose breath actuated inhalers CFC free

medium DHSC MSN

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Expected resolution: December 2025

Amiodarone 200mg tablets

medium DHSC MSN

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Abidec® Multivitamin drops

medium DHSC MSN

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Vials of Humulin® I, Humulin® S, Humulin® M3, and Humalog® Mix25 are being discontinued.

medium DHSC MSN

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Expected resolution: April 2026

Vial presentations of Hypurin® Porcine Isophane, Hypurin® Porcine Neutral and Hypurin® Porcine 30/70 Mix are being discontinued

medium DHSC MSN

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Expected resolution: September 2025

Isosorbide mononitrate 10mg tablets (immediate-release)

medium DHSC MSN

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Estradiol (Progynova® TS) 50micrograms/24hours and 100micrograms/24hours transdermal patches

medium DHSC MSN

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Updated Levemir® (insulin detemir) FlexPen® 100units/ml solution for injection 3ml pre-filled pens and Levemir® Penfill 100units/ml solution for injection 3ml cartridges

medium DHSC MSN

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Expected resolution: of 2026

Repaglinide 500microgram,1mg and 2mg tablets

medium DHSC MSN

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Admelog® (insulin lispro)

medium DHSC MSN

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Expected resolution: March 2026

Exenatide (Bydureon® BCise® ) 2mg/0.85ml prolonged-release suspension for injection pre-filled pen

medium DHSC MSN

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Dalivit® Oral Drops

medium DHSC MSN

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Mometasone (Asmanex Twisthaler®) 200micrograms/dose dry powder and 400micrograms/dose dry powder inhalers

medium DHSC MSN

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Amiodarone 100mg and 200mg tablets

medium DHSC MSN

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Propranolol 80mg and 160mg modified release capsules

medium DHSC MSN

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Nifedipine (Fortipine® LA) 40mg modified-release tablets

medium DHSC MSN

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Fiasp® FlexTouch® (insulin aspart) 100units/ml solution for injection 3ml pre-filled pens

medium DHSC MSN

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Tresiba® (insulin degludec) FlexTouch® 100units/ml solution for injection 3ml prefilled pens

medium DHSC MSN

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Nifedipine (Adipine® XL) 30mg and 60mg modified-release tablets

medium DHSC MSN

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Latanoprost 50micrograms/ml / Timolol 5mg/ml (Fixapost® ) eye drops 0.2ml unit dose preservative free

medium DHSC MSN

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Clonidine (Catapres®) 100microgram tablets

medium DHSC MSN

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Genotropin® (somatropin) 5.3 mg and 12 mg powder and solvent for solution for injection

Medium DHSC MSN

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Hypurin® Porcine 30/70 Mix (insulin isophane biphasic porcine) 100units/ml suspension for injection 3ml cartridges

Medium DHSC MSN

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Buprenorphine/naloxone (Suboxone® ) 2mg/500microgram and 8mg/2mg sublingual tablets

Medium DHSC MSN

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Oxybutynin (Kentera® ) 3.9mg/24hours transdermal patches

Medium DHSC MSN

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Lisdexamfetamine (Elvanse®) capsules

Active DHSC MSN

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Pancreatic enzyme replacement therapy (PERT)

Active DHSC MSN

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Methylphenidate prolonged-release tablets

Active DHSC MSN

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Expected resolution: October 2024

Creon® Micro Pancreatin 60.12mg gastro-resistant granules

Active DHSC MSN

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Trandate® (labetalol) 50mg tablets

Active DHSC MSN

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Sodium fusidate (Fucidin® ) 250mg tablets and fusidic acid (Fucidin® ) 250mg/5ml oral suspension

Active DHSC MSN

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Xylocaine® (lidocaine) 10mg spray

Active DHSC MSN

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Camellia sinensis extract (Catephen® ) 10% ointment Fluorouracil (Efudix® ) 5% cream Imiquimod (Aldara® 5% and Zyclara® 3.75%) cream 250mg sachets

Active DHSC MSN

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Quetiapine 50mg, 150mg, 200mg, 300mg and 400mg modified-release tablets

Active DHSC MSN

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Desmopressin 10microgram/dose nasal spray

Active DHSC MSN

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Expected resolution: September 2025

Levofloxacin 250mg and 500mg tablets

Active DHSC MSN

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Discontinuation of Subutex® and Suboxone® tablets

Active DHSC MSN

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Discontinuation of Subutex® and Suboxone® tablets

Active DHSC MSN

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SSP61 - Creon® 25000 gastro-resistant capsules further extended

Active DHSC MSN

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Expiry of SSP084 Adipine® XL 30mg MR tablets and SSP085 Adipine® XL 60mg MR tablets

Active DHSC MSN

Serious Shortage Protocol active for Adipine® XL 30mg MR tablets (PDF:199KB). Pharmacists may supply alternatives without GP referral.

Expected resolution: 19 December 2025

SSP60 - Creon® 10000 gastro-resistant capsules further extended

Active DHSC MSN

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Data sources: DHSC Medicine Supply Notifications · NHSBSA Serious Shortage Protocols · NHS England
Page last updated: 7 February 2026. Data checked daily.
🏥 Data sourced from official DHSC and NHS England publications · Updated daily · Free service