What to do first
Step 1: Decide how urgent this is
Before choosing a route, work out whether this is a same-day clinical risk or an administrative problem that can wait until your GP or pharmacy opens. The answer depends on the medicine, the condition, how many doses you have left, and what your clinician has told you about missed doses.
Treat it as urgent if you are due to miss a dose of a medicine that you have been told not to stop, or if you already have symptoms because you have missed treatment. Examples that often need faster escalation include insulin, anti-seizure medicines, anticoagulants, transplant or immunosuppressant medicines, oral steroids, Parkinson's medicines, opioid substitution therapy, lithium, some heart medicines and some mental health medicines.
If you are unsure, do not guess. Speak to a pharmacist, use NHS 111 online, call 111, or use emergency services if symptoms are severe or life-threatening.
Step 2: Ask a pharmacy about emergency supply
NHS guidance says pharmacies can provide certain emergency prescription medicines even when you do not have a prescription, but this is not automatic. The pharmacist has to decide whether an emergency supply is legally and clinically appropriate. They may ask what medicine you take, when it was last prescribed, when the next dose is due, what dose you take and whether there are safety concerns.
Bring or show as much evidence as possible:
- the medicine box, label, repeat slip or NHS App record
- the exact medicine name, strength, formulation and dose
- your GP surgery or prescriber details
- proof of identity if requested
- details of allergies, pregnancy, breastfeeding or recent medicine changes
You may need to pay when a pharmacy supplies medicine urgently without a prescription. If the pharmacist cannot supply it, ask them what route they recommend next and whether another pharmacy, NHS 111 or your GP out-of-hours service is more appropriate.
Step 3: Use NHS 111 for repeat prescription emergencies
If you normally receive the medicine on repeat prescription and you have run out, NHS guidance points patients to the NHS emergency prescriptions route. NHS 111 online asks questions about where you are, what medicine you need, and when the next dose is due, then directs you to the most appropriate service.
NHS 111 may direct you to a pharmacy, another local NHS service, or urgent clinical support depending on your answers. NHS 111 online is available in England; the service also links to equivalent routes for Northern Ireland, Scotland and Wales.
Use NHS 111 rather than waiting for routine GP opening if you are going to miss an important dose before normal services reopen. Use emergency services if you have symptoms that suggest immediate danger.
Step 4: Contact your GP or out-of-hours service
If the problem is not immediate but you need a prescription issued or changed, contact your GP surgery. If the surgery is closed, the answerphone should usually explain how to access out-of-hours help. NHS 111 can also route you to out-of-hours services when appropriate.
This route is often better than a pharmacy-only route when:
- the medicine is not on repeat prescription
- the pharmacy cannot legally supply it as an emergency supply
- your dose or medicine has recently changed
- you need a different formulation or brand because of a shortage
- the medicine is managed by a specialist or shared-care agreement
When contacting the surgery, be specific: "I have one dose left of [medicine, strength and formulation]. My pharmacy cannot supply it today. Can a prescriber review an urgent prescription or alternative?" That is more useful than "I need medication urgently."
Step 5: Know when urgent treatment centres or A&E fit
NHS guidance lists urgent treatment centres as one possible route for emergency prescription medicine after a consultation. They are not a replacement for routine repeat prescribing, but they can be appropriate when you need clinical assessment and cannot wait for GP opening.
A&E should be reserved for emergencies. Use it when the medicine issue is part of a serious or life-threatening situation, such as severe symptoms, a high-risk missed medicine with immediate danger, or a clinician/NHS 111 telling you to attend. For routine repeat medicines, a pharmacy, NHS 111 or out-of-hours GP route is usually more appropriate.
Step 6: If the problem is a shortage, ask about SSPs
An emergency prescription route does not automatically solve a national shortage. If the medicine is unavailable because of a supply issue, ask the pharmacist whether there is a Serious Shortage Protocol, or SSP, for the exact medicine. The NHSBSA active SSP list is the official place to check current protocols.
If an SSP is active, the pharmacist can supply only what the protocol allows and only where it is appropriate. If no SSP applies, your GP, specialist or other prescriber may need to decide whether a different medicine, strength, formulation or brand is safe.
You can also search the MediWatch shortage tracker or the A-Z medicine shortage pages to see whether there is a national supply signal and whether the page links to official source information.
What to say at the pharmacy or to NHS 111
| Question | Why it matters |
|---|---|
| "I take [medicine], [strength], [formulation], [dose]. Can you check emergency supply options?" | Gives the pharmacist the details needed to assess whether supply is possible. |
| "I have [number] doses left and my next dose is due at [time]." | Helps the service judge urgency. |
| "This is normally prescribed by [GP/specialist] and last supplied on [date]." | Supports verification and safe decision-making. |
| "The pharmacy says it may be a shortage. Is there an SSP or safe alternative route?" | Separates a supply issue from a lost-prescription issue. |
Common mistakes to avoid
- Do not split, crush, open, stretch or double doses unless a pharmacist or prescriber confirms it is safe.
- Do not use someone else's medicine, even if it has the same name.
- Do not buy prescription-only medicine from an unregulated website.
- Do not leave high-risk medicines until the final dose before asking for help.
- Do not use A&E for routine repeat prescription admin unless the medicine issue has become an emergency.
FAQ
A pharmacy may be able to provide certain emergency prescription medicines without a prescription, but it is not automatic. The pharmacist must decide whether the legal and clinical criteria are met and whether the medicine is suitable for emergency supply.
If you normally receive the medicine on repeat prescription and have run out urgently, NHS guidance points patients to the NHS 111 online emergency prescription service, a pharmacy, an urgent treatment centre, the GP surgery or A&E for emergencies.
You may need to pay when a pharmacy supplies emergency medicine without a prescription. If a prescription is issued through NHS routes, normal NHS prescription charge and exemption rules may apply.
NHS 111 online can direct you to the right urgent prescription or medicine route. It may refer you to a pharmacy or another service depending on your answers and local availability.
Tell the pharmacist or prescriber that the issue may be a shortage, ask whether a Serious Shortage Protocol applies, and check official shortage information. Do not self-substitute or stretch doses while waiting.
Related guides
Prescription out of stock
The full step-by-step action plan
Your rights when medicine is unavailable
What to ask and where to escalate
Private prescriptions
When private routes help and when they do not
Travelling with medication
Plan before you run out away from home
See also
Prescription out of stock: what to do
Practical actions while arranging emergency supply
Mental health medication availability
High-risk category where continuity matters
A-Z medicine shortage pages
Find real-time status for your medicine
Written by the MediWatch editorial team. Reviewed for source alignment on 7 May 2026. This page is information, not medical advice. Always follow your pharmacist, GP, specialist, NHS 111 or urgent-care advice for your own medicine. Report an accuracy issue.