Pancreatic enzyme replacement therapy Shortage UK 2026

Current supply status and alternatives for Pancreatic enzyme replacement therapy

Source data checked 12 November 2026, 06:18 UTC

Shortage

Active shortage — confirmed in official DHSC / NHSBSA data (official data last checked 12 November 2026, 06:18 UTC).

National Patient Safety Alert: Shortage of Pancreatic enzyme replacement therapy (PERT) – Additional actions

Limited supply

Expected: see the official wording

The details differ by product, strength or date. Check yours in the official wording below.

The notice says

Creon® 10,000 and 25,000 capsules remain in limited supply until 2026.
Nutrizym® 22 capsules and Pancrex V® capsules and powder are intermittently available but are unable to fully cover the gap in supply.

Instructions in the notice for healthcare professionals (5)

Clinicians should continue to follow the actions set out in the National Patient Safety Alert (NatPSA/2024/007/DHSC) issued on 24th May 2024.
NHS provider trust pharmacy procurement teams should ensure that where quantities greater than current demand are required, unlicensed imports should be considered.
To ensure that patients are not left without PERT, Integrated Care Boards (ICBs) should:
put in place a local mitigation plan for instances when patients are unable to obtain stock from their community pharmacy or dispensing GP.
cascade any local management plan to all community pharmacies and GP practices within the region, as well as local trust pharmacy teams.

From the official notice: Patient safety alert.

Don't stop or change your medicine on your own. Ask your pharmacist or GP.

Track Pancreatic enzyme replacement therapy

We'll email you only when this medicine's status actually changes — including when its official shortage notice ends. Most weeks that's nothing, and that's good news. Your first 5 tracked medicines are free.

Nearby pharmacies to call about Pancreatic enzyme replacement therapy

Enter your postcode to see nearby NHS-registered pharmacies. Stock is not confirmed.

MediWatch does not guarantee live local stock. Call the pharmacy to confirm before travelling, and never stop or change medication without medical advice.

Where to get Pancreatic enzyme replacement therapy

Speak to your pharmacist. They may be able to order it from another wholesaler, or suggest a different strength or form.
Ask your GP or prescriber about an alternative if it can't be sourced. Don't stop or switch medicine on your own.
Try other pharmacies. Stock varies between pharmacies. Find nearby pharmacies to call or use the NHS Find a pharmacy service (opens in a new tab).

Pancreatic enzyme replacement therapy is used for various medical conditions. Official DHSC / NHSBSA data list an active shortage notification for National Patient Safety Alert: Shortage of Pancreatic enzyme replacement therapy (PERT) – Additional actions. Other forms of this medicine are not named in it — details above.

What to Do If You're Affected

Contact your pharmacy as soon as possible — don't wait until you run out
Ask your pharmacist if a Serious Shortage Protocol (SSP) is active
If your pharmacy can't supply it, speak to your GP or prescriber
Try other local pharmacies who may have different stock
Sign up for MediWatch alerts to track this shortage

⚠️ Important: NHS Listed Medication Safety

Urgency: Do not stop taking your prescribed medication without consulting your doctor, even if supply is disrupted.

What to do: Contact your GP or pharmacist as soon as you become aware of a shortage affecting your medication. The earlier you act, the more options you will have.

Tip: Phone ahead before visiting the pharmacy. Many pharmacies can check stock levels by phone and may be able to order your medication from their wholesaler.

Frequently Asked Questions

Is Pancreatic enzyme replacement therapy in shortage in the UK in 2026?

Yes — official DHSC / NHSBSA data list an active shortage notification for National Patient Safety Alert: Shortage of Pancreatic enzyme replacement therapy (PERT) – Additional actions. Other forms of Pancreatic enzyme replacement therapy are not named in it. Sign up for MediWatch alerts to be notified of any changes.

What is Pancreatic enzyme replacement therapy used for?

Pancreatic enzyme replacement therapy is commonly prescribed in the UK for various medical conditions. It is dispensed through NHS pharmacies across the country.

What should I do if I can't get Pancreatic enzyme replacement therapy from my pharmacy?

Ask your pharmacist whether a Serious Shortage Protocol (SSP) covers it and what that protocol allows: each one sets out exactly what can be supplied. If your pharmacy can't supply it, speak to your GP or prescriber, and don't stop or change your medicine on your own. Try other local pharmacies as stock levels vary by location.

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Generated from official data: 12 November 2026 · Report an accuracy issue
Data sources: DHSC Medicine Supply Notifications · NHSBSA Serious Shortage Protocols · MHRA alerts
MediWatch is not medical advice. Always follow your prescription label and ask a pharmacist, GP, specialist, NHS 111, or emergency services if you are unsure or unwell. Data checked daily.