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Alternatives to Estradot during the UK shortage: what the official notice says

Estradot is in short supply. Here is exactly what the official notice says is still available, what your pharmacist may be allowed to supply instead, and the questions to ask. Never switch medicines yourself.
Source data checked 12 November 2026, 06:18 UTC

Quick answer: An NHS Serious Shortage Protocol is in place for Estradot. It lets your pharmacist supply it differently from your prescription, but only in the way the protocol sets out.

Do not switch, stop or change Estradot yourself. Whether a different strength, form, brand or medicine is right for you is a decision for your pharmacist or prescriber, who knows your history.

What the official notices say about alternatives to Estradot

Estradot® 25 microgram patches: Serious Shortage Protocol (NHSBSA SSP082)

Issued 03 April 2025 · Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

What this protocol allows: Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

Source: NHSBSA, NHSBSA SSP082. Read the protocol itself before relying on it.

Estradot® 100 microgram patches: Serious Shortage Protocol (NHSBSA SSP081)

Issued 19 December 2024 · Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

What this protocol allows: Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

Source: NHSBSA, NHSBSA SSP081. Read the protocol itself before relying on it.

Estradot® 75 microgram patches: Serious Shortage Protocol (NHSBSA SSP080)

Issued 19 December 2024 · Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

What this protocol allows: Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

Source: NHSBSA, NHSBSA SSP080. Read the protocol itself before relying on it.

Estradot® 50 microgram patches: Serious Shortage Protocol (NHSBSA SSP079)

Issued 19 December 2024 · Protocol until: 08 January 2027

An NHS Serious Shortage Protocol is in place until 08 January 2027.

What this protocol allows: Under this protocol, your pharmacist may give you Evorel® or Estraderm® MX patches of the same strength instead of Estradot®, one for one and for the full amount prescribed, if you agree. It applies to people aged 18 and over, and your prescriber or GP practice is told. Your pharmacist will tell you what to look out for, such as breakthrough bleeding, skin irritation or patches not sticking; if side effects carry on, speak to your prescriber.

Source: NHSBSA, NHSBSA SSP079. Read the protocol itself before relying on it.

Is a different medicine an option for me?

Only your prescriber can decide that. MediWatch does not suggest equivalents: medicines that look similar can differ in dose, how they are taken, interactions and side effects. If your pharmacy can't supply Estradot, ask your GP or prescriber what they recommend for you. The BNF and the NHS medicines A to Z are the official references they use.

What to ask your pharmacist

Already run out? Don't ration or stretch what you have. A pharmacist may be able to make an emergency supply, or use the NHS 111 emergency supply route. Call 999 if missing your medicine has caused severe symptoms.

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Sources and review: NHSBSA SSP082 · NHSBSA SSP081 · NHSBSA SSP080 · NHSBSA SSP079 · NHSBSA Serious Shortage Protocols · BNF (NICE): Estradot · NHS medicines A to Z · DHSC: medicine supply management
Written by the MediWatch editorial team and checked against the official sources above on 12 November 2026. This page is information, not medical advice. Always follow your pharmacist, GP, specialist, NHS 111 or urgent-care advice for your own medicine. Report an accuracy issue.
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Checked against official UK sources
DHSC · NHS · NHSBSA · legislation.gov.uk

This page was written by the MediWatch editorial team and checked for accuracy against NHS, NHSBSA and legislation.gov.uk guidance. Shortage information comes from official DHSC medicine supply notifications and NHSBSA Serious Shortage Protocols. See our editorial policy and data sources.

🏥 Data sourced from official DHSC, NHSBSA and MHRA publications · Updated daily · Free service