Digestive Medication Shortage UK

8 active shortages tracked

Updated 27 March 2026 from official DHSC & NHS data

Digestive medication shortages have been particularly acute for Creon (pancreatic enzymes), which is essential for patients with cystic fibrosis and pancreatitis. Multiple Serious Shortage Protocols are active.

Current Active Shortages (8)

Creon® 25000 capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Creon® 25000 capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

⚠️ Resolution date passed — supply status unconfirmed. Check with your pharmacist.

Creon® 10000 capsules

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Creon® 10000 capsules (PDF:193KB). Pharmacists may supply alternatives without GP referral.

⚠️ Resolution date passed — supply status unconfirmed. Check with your pharmacist.

Salazopyrin® 500mg tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin® 500mg tablets (PDF:244KB). Pharmacists may supply alternatives without GP referral.

⚠️ Resolution date passed — supply status unconfirmed. Check with your pharmacist.

Salazopyrin® 500mg EN tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin® 500mg EN tablets (PDF:160KB). Pharmacists may supply alternatives without GP referral.

⚠️ Resolution date passed — supply status unconfirmed. Check with your pharmacist.

Salazopyrin 500mg EN tablets

Serious Shortage NHSBSA SSP

Serious Shortage Protocol active for Salazopyrin 500mg EN tablets (PDF:151KB). Pharmacists may supply alternatives without GP referral.

⚠️ Resolution date passed — supply status unconfirmed. Check with your pharmacist.

Creon® Micro Pancreatin 60.12mg gastro-resistant granules

Active DHSC MSN

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Creon® Micro Pancreatin 60.12mg gastro-resistant granules • Creon® Micro Pancreatin 60.12mg gastro-resistant g

SSP61 - Creon® 25000 gastro-resistant capsules further extended

Active DHSC MSN

In response to a significant ongoing disruption to the supply of Creon® 25000 gastro-resistant capsules , a Serious Shortage Protocol (SSP) has been issued by the Department of Health and Social Care

SSP60 - Creon® 10000 gastro-resistant capsules further extended

Active DHSC MSN

In response to a significant ongoing disruption to the supply of Creon® 10000 gastro-resistant capsules, a Serious Shortage Protocol (SSP) has been issued by the Department of Health and Social Care (

What to Do If Affected

Contact your specialist team immediately
Don't reduce Creon doses without dietitian advice
Ask about alternative pancreatic enzyme products
Report shortages to your CF team if applicable
Contact Crohn's & Colitis UK: 0300 222 5700

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Data sources: DHSC Medicine Supply Notifications · NHSBSA Serious Shortage Protocols · NHS England
Page last updated: 27 March 2026. Data checked daily.